On this page about Prodrug:
A prodrug is a pharmacological substance (drug) which is administered in an inactive (or significantly less active) form. Once administered, the prodrug is metabolised in vivo into the active compound.
How to say "Prodrug" in other languages:
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(Chinese) | 前体药物 |
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(German) | Prodrug |
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(Italian) | Profarmaco |
L-DOPA (levodopa, 3,4-dihydroxy-L-phenylalanine). As a drug it is used to treat parkinsonism. L-DOPA is able to pass the blood-brain barrier as a prodrug and is decarboxylated in the brain to the neurotransmitter dopamine by the enzyme aromatic-L-amino-acid decarboxylase. In this way, L-DOPA can...
prodrug and is converted in vivo to the active form fosinoprilat...
enalaprilat with ethanol to produce enalapril . As a prodrug, enalapril is metabolised in vivo to...
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